hrp0089p1-p202 | Pituitary, Neuroendocrinology and Puberty P1 | ESPE2018

Long-acting Octeotride Treatment in Children with Neurofibromatosis Type 1 - Optic Pathway Tumors and Growth Hormone Excess

Guiraldo Paula Ximena Molina , Hernandez Hector Salvador , Bartomeu Joan Prat , Paula Casano Sancho

Introduction: Growth hormone excess (GHE) in children with neurofibromatosis type 1 (NF-1) has been reported in some sporadic cases. Whether GHE stimulates progressive optic pathway glioma (OPG) growth is of concern. The prevalence of GHE in NF-1 has not been described and the scheme treatment has not been well characterized.Objective: To describe in children with NF-1/OPG and GH excess the treatment regimen and long term response to long- acting octeotr...